Publications by Biopta

Publications by Biopta

A novel role for CCR3 in promoting airways hyperreactivity; Role for CCR3-muscarinic M3 receptor heterodimers. European Respiratory Journal

Effects of Recombinant Human Type I Pancreatic Elastase on Human Atherosclerotic Arteries. J Cardiovasc Pharmacol 2014;64:530–535 Burke, S.K. et al.

Tumor stromal architecture can define the intrinsic tumor response to VEGF-targeted therapy. Clinical Cancer Research 19 (24) 6943-56 (2013) Smith N.R. et al.

The Use of Functional Human Tissues in Drug Development. Cell and Tissue Banking 12: 31-32 (2011). Bunton D.C

An antibody targeted to VEGFR-2 Ig domains 4-7 inhibits VEGFR-2 activation and VEGFR-2-dependent angiogenesis without affecting ligand binding. Molecular Cancer Therapeutics 10: 770-783 (2011) Kendrew J. et al.

The Use of Functional Human Tissues in Drug Development. ATLA 38: 27-30 (2010). Bunton D.C.

A Novel System for the Investigation of Microvascular Dysfunction including Vascular Permeability and Flow Mediated Dilation in Pressurised Human Arteries. Pharmacological and Toxicological Methods 62: 40-46 (2010). Moss E., Lynagh S., Smith D., Kelly S., McDaid A., Bunton D.C.

Could Fresh Human Tissue play a Key Role in Drug Development? ATLA 1: 5-10 (2009). Bunton D.C.

Evaluation of Equine Laminar Vein Function: Harvesting, Dissection and the use of Functional Methods to Distinguish between Veins and Arteries. Pharmacological and Toxicological Methods 57: 92-99 (2008). Keen J.A., Hillier C., McGorum B.C., Bunton D.C., Nally J.E.

Functional Human Tissue. Drug Discovery Today (12): 382:388 (2007). Bunton D.C

The Clinical Relevance of Adrenomedullin: A Promising Profile? Pharmacology and Therapeutics 103: 179-201 (2004). Bunton D.C., Petrie M.C., Hillier C., Johnston F., McMurray J.J.V.

Relaxation to Bradykinin in Bovine Pulmonary Supernumerary Arteries can be mediated by both a Nitric Oxide-Dependent and –Independent Mechanism. British Journal of Pharmacology 137: 538-544 (2002). Tracey A., Bunton D.C., Irvine J., MacDonald A., Shaw A.M.

Regulation of Sensitivity to 5-hydroxytryptamine in Pulmonary Supernumerary but not Conventional Arteries by a 5HT1D- like Receptor. European Journal of Pharmacology 408: 69-82 (2000). Shaw A.S., Bunton D.C., Brown T., Irvine J., MacDonald A.

5-hydroxytryptamine- and U46619-Mediated Vasoconstriction in Bovine Pulmonary Conventional and Super-Numerary Arteries: Effect of Endogenous Nitric Oxide. Clinical Science 98: 81-89 (2000). Bunton D., MacDonald A., Brown T., Tracey A., McGrath J.C.

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