Skin

Skin

Biopta can access fresh heathy tissue from operations such as abdominoplasties.  As well as a rich source of subcutaneous resistance vessels for vascular studies, this tissue section is also used to provide full thickness biopsies of various sizes. These are cultured in media for a number of days to provide a biological test system for investigative biology and compound testing.   For example, they can stimulated to release IL-17, providing a test system for a pathway that is implicated in the pathogenesis of psoriasis.

Biopta also has the ability to source patients with skin condition such as psoriasis and atopic dermatitis.  These patients are recruited into clinical sites where they donate multiple biopsies for the projects at Biopta.  The data from these valuable diseased tissues thus complements the information from the healthy human tissue systems and provides the researcher with translational models to answer many drug discovery questions.

 

 

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