Unwanted effects on the GI tract can also be detected using our human tissue models. Effects on permeability can be assessed using our Ussing Chamber methodology. It is also possible to determine the effects of your test compound on the enteric nervous system or ‘mini-brain’, as this is where much of the regulation of the GI tract occurs. Our organ bath model can therefore be used to determine adverse effects on the gut motility. Inflammation of the gut is also a regular unwanted side effect of many test compounds, which can be detected using our mucosal organoculture model.
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