In vitro Drug Discovery Services
Biopta has unrivalled expertise in classical pharmacological techniques, including organ baths and small vessel wire and perfusion myography to assess functional responses such as a constriction or dilation of cardiac muscle or smooth muscle.
Biopta is able to provide in vitro pharmacology support throughout early development, from lead identification to preclinical safety. Based on your stage of development we can advise on the most relevant assay and selection of tissues and can provide information on;
- compound profiling for agonist or antagonist activity
- potency and efficacy
- onset and duration of action
- unwanted adverse effects
- release of biomarkers such as cytokines or superoxide